Saturday, 27 February, 2021


Covid vaccine: Single dose Covid vaccine 66% effective

Covid vaccine: Single dose Covid vaccine 66% effective Single-dose COVID-19 vaccine could be 85% effective, available next month
Patty Aguilar | 31 January, 2021, 08:31

"So we're able to get a lot more immune response than a typical single shot", he said. The two vaccines showed an efficacy of around 95% in trials conducted primarily in the USA before the new virus versions were identified in other countries.

Pfizer and BioNTech also said earlier this month that early findings showed that their vaccine will likely be effective against the new variants of the coronavirus.

"These topline results with a single-shot COVID-19 vaccine candidate represent a promising moment", said a statement by Dr. Paul Stoffels, chief scientific officer at Johnson & Johnson.

Crucially, it looked at giving just one dose of the vaccine, which makes it significantly easier to roll out than those requiring two.

South Africa plans to vaccinate more than 40 million people, or 67% of its population, in order to achieve "herd immunity" that would assist in slowing down the pandemic, the minister said.

The company says it plans to apply to the Food and Drug Administration for emergency use authorization to distribute the vaccine.

Nevertheless, Fauci said the decreased efficacy rates underscore the need to follow variants closely, and to accelerate vaccination efforts before new, and even more risky, mutations arise.

"This is not the case yet ... but I think it's a very high likelihood that one day that will happen", Bourla said at the World Economic Forum.

"We knew that to a certain extent, but it's also better and very confirming that we can see that now in the clinic", Stoffels said in an interview.

The Phase 3 clinical trials included about 44,000 participants in the U.S., Latin America and South Africa.

South Africans will be required to register on this system before they receive a COVID-19 vaccine, the Department of Health has stated.

However the vaccine was just 57% effective in the South African part of the trial, where a new version of the coronavirus is spreading.

Another highly transmissible variant first discovered in the United Kingdom and now in more than half of U.S. states has been less able to evade vaccine efficacy than its South African counterpart.

The U.S. government has preordered about 100 million doses, but Johnson & Johnson only expects to have fewer than 10 million doses available for February.

Germany's decision contradicts the United Kingdom government's move to administer doses to people over 65.

The vaccine was one of six candidates backed by a USA government project formerly known as Operation Warp Speed, which has provided the company with US$1.75 billion (S$2.33 billion).

The safety profile of Janssen's Covid-19 vaccine was deemed to be consistent with other products developed using the J&J subsidiary's AdVac technology, including its Ebola vaccine.

Johnson & Johnson's data still needs to undergo review by the FDA.

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