Saturday, 23 January, 2021


This Bacteria Lurking in Your Gut May Worsen COVID Symptoms, Research Finds

Science Times- 6 Months After COVID-19 Infection 76% of Patients Still Experience Symptoms—Study Study: Most Covid-19 patients have at least 1 symptom 6 months on
Patty Aguilar | 13 January, 2021, 07:57

The research was conducted among 1,733 out of 2,469 patients who were discharged from January to May from Jinyintan Hospital, one of the earliest designated hospitals for critical COVID-19 patients in Wuhan, central China's Hubei Province. Researchers followed nearly 2,000 Wuhan patients who were hospitalized with COVID-19 and found that the most common post-infection symptoms were fatigue or muscle weakness and sleep problems. More than six in 10 people (63%) of the 1,733 patients examined experienced this problem.

A new study recently found that 'fatigue or muscle weakness, ' were among the common long-term COVID symptoms, while some also reported difficulties sleeping. Follow-up visits were done, and the median follow-up time was 186 days.

Aside from lingering symptoms, study authors discovered patients who had suffered from more severe COVID infections are more likely to now have impaired lung function.

They said longer term multidisciplinary research being conducted in the United States and Britain would help improve understanding and help develop therapies to "mitigate the long-term consequences of Covid-19 on multiple organs and tissues". The scientists concluded that most of the hospitalised patients faced at least one symptom after getting discharged, which highlights the need for proper post-discharge care. "Our work also underscores the importance of conducting longer follow-up studies in larger populations in order to understand the full spectrum of effects that COVID-19 can have on people", says Professor Bin Cao from National Center for Respiratory Medicine, China-Japan Friendship Hospital, and Capital Medical University in a media release. The former patients also underwent physical examinations and a 6-minute walking test and received blood tests. 390 patients had further tests, including an assessment of their lung function. Of the 86 participants needing a ventilator in Jin Yin-tan Hospital, 56 percent now suffer from diffusion impairment.

Healthcare professionals are becoming increasingly concerned that the long-term effects experienced by those COVID-19 patients who were hospitalised, may be underestimated. And he's seen similar issues among patients at his hospital.

The findings also suggest that patients with more severe disease performed worse in the six-minute walking test. Researchers also found that 13 per cent of the patients whose kidney function was normal while in the hospital had reduced kidney function in their follow-up.

Furthermore, the research also looked at more than 90 patients whose levels of blood antibody were recorded "at the height of the infection" as part of another test. The study also reveals that women have a higher risk of being affected by the virus than men.

Patients who had recovered for six months are seeing their seropositivity of the neutralizing antibodies significantly decreased to an average of 58.5 percent compared with that at the acute phase of 96.2 percent, the study shows, meaning they could be infected again.

"Associations between gut microbiota composition, levels of cytokines, and inflammatory markers in patients with COVID-19 suggest that the gut microbiome is involved in the magnitude of COVID-19 severity possibly via modulating host immune responses", the study's authors wrote.

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