Saturday, 27 February, 2021


COVID-19 vaccine could come in late October

Materials being packed and sent out UNICEF UNI325740/Montico
Bennie Garza | 05 September, 2020, 04:42

The coronavirus vaccine that Russian Federation developed is safe and elicited "strong humoral and cellular immune responses" in human trials.

Results of a oronavirus vaccine trial in Russian Federation, showed an antibody response within three weeks in all participants tested in phase two of the study, according to findings released Friday.

"Further investigation is needed of the effectiveness of this vaccine for prevention of COVID-19". Doctors studied 76 healthy volunteers aged between 18 and 60, over six weeks.

These vaccines aim to stimulate both arms of the immune system - antibody and T cell responses - so they attack the virus when it is circulating in the body, and attack cells infected by SARS‐CoV‐2.

AstraZeneca further stated that the trials are also planned in Russian Federation, where there have been a million coronavirus cases.

Russian Federation has said it expects to produce between 1.5 million and 2 million doses per month of its potential COVID-19 vaccine by the end of the year, gradually increasing production to 6 million doses a month.

"If we start setting nation against nation, vaccine against vaccine, and company against company, this is going to completely undermine any kind of rational response", he said.

There were 20 participants each in the frozen and freeze-dried vaccine groups, the Lancet study noted.

But with the results now published for the first time in an global peer-reviewed journal, and with a 40,000-strong later-stage trial launched last week, a senior Russian official said Moscow had faced down its critics overseas.

Adverse events were mostly mild, with the most common adverse events being pain at the injection site, hyperthermia, headache, asthenia, and muscle and joint pain, said the study.

"The study was not randomised, and it was not large enough to detect rarer safety issues".

Most experts say that it is reasonable to expect the Phase 3 tests to be completed by year's end.

Following an announcement, earlier this week, 30,000 volunteers from the United States were taking part in the final stages of the COVID-19 vaccine trial. Their candidates are all in late-stage clinical trials.

In the phase 2, which began no earlier than five days after the phase 1 trial began, participants received the full two-part vaccine - they received a prime vaccination with the rAd26-S component on day 0, followed by a booster vaccination with rAd5-S component on day 21.

According to the World Health Organization, 34 vaccine candidates worldwide are now in the various phases of being tested on humans, while a further 142 are in pre-clinical evaluation.

"How can you justify a substandard or lesser review for something that would be injected in tens of millions, maybe hundreds of millions of Americans?" said Peter Hotez, a USA health and vaccines expert at Baylor College of Medicine in Texas.

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