Sunday, 21 October, 2018


Cleaning Product Use Alters Infant Microbiome to Cause Obesity

Household disinfectants could be making kids overweight, study says Alberta study finds household cleaners may cause obesity in young children
Patty Aguilar | 19 September, 2018, 15:58

"Antibacterial cleansing merchandise occupy the skill to vary the environmental microbiome and alter possibility for child chubby", the authors quit.

The team analyzed the gut microbiota of 757 infants ages 3 to 4 months and then their weight at ages 1 and 3 years, according to Medical Xpress. It also surveyed their exposure to disinfectants, detergents and eco-friendly products used in the home. The association was found in the new study too since the infants who had higher levels of Lachnospiraceae also had a higher body mass index (BMI) by the time they were three years old.

Relationship with adjusted gut flora in babies 3-4 months old were strongest for visit utilization of family unit disinfectants, for example, multi-surface cleaners, which indicated lower levels of Haemophilus and Clostridium microbes, however, larger amounts of Lachnospiraceae.

Specifically, antibacterial cleaners were linked to an increase in gut levels of Lachnospiraceae in infants.

The link between disinfectants, gut bacteria, and weight is compelling, and it should be studied more.

"We found that infants living in households where disinfectants were used at least weekly were twice as likely to have higher levels of the bacteria called Lachnospiraceae at three to four months of age", said Anita Kozyrskyj, a U of A pediatrics professor and lead on the investigation into how adjustment of infant gut microbiome impact health.

The study notes that infants in households with high use of environmentally friendly cleaners had decreased odds of becoming overweight or obese - but that was not related to their gut microbiome as an infant.

The bacteria Lachnospiraceae are "a normal component of our gut microbiota", Anita Kozyrskyj, senior author of the study and a University of Alberta pediatrics professor, said in a CMAJ podcast. "However, we found no evidence that these gut microbiome changes caused the reduced obesity risk", Kozyrskyj said.

The study provides novel information regarding the impact of these products on infant gut microbial composition and outcomes of increased weight in the same population.

Reference Postnatal exposure to household disinfectants, infant gut microbiota and subsequent risk of overweight in children. Rather, Kozyrskyj speculated that mothers who used eco-friendly products may have had a healthier diet and so healthier microbiomes during pregnancy creating a positive result in newborn's microbiome, and later weight gain.

"Based on our study's finding, we recommend against the frequent use of disinfectant cleaners in households with infants and suggest that parents consider alternative cleaning products". "Attributable to this is a first glance, confirmatory analysis in other cohorts is required", Dr. Kozyrskyj acknowledges.

And "higher frequency of use of disinfectant was associated with higher abundance of Lachnospiraceae", said Kozyrskyj. "I want to emphasize that our findings on the disinfectant use were at the higher end of use". Exposure to various cleaning products at home were also recorded.

The CHILD Study is collecting a range of health, lifestyle and environmental exposure information from almost 3,500 mothers and children from pregnancy to age five; it spans four provinces (BC, AB, MB and ON).

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